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简介 ZN ?P4#ZS 人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 'c<@SVF{Zz g/q$;cB 模型 0OMyE9jJJ NW9k.D% 模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 1*x4T%RF$ CW=-@W7 Table 1. AZ眼睛模型的定义 Xklp6{VH9 在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. 4[!&L:tR /j'We-C 光源 [<sBnHbvQ. Ac.z6]p 多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 9&W\BQ 5Wi5`8m R^F99L 图1. 光源和提示信息使用 `4&\ %9 除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 {-S0m= A?;/]m; 在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 ,7M9f &K^h'>t' 图2. 字母F光源的设定方法光 xL>0&R @/JGC%! 图3. 字母F在视网膜上位置点列图 ?XGZp?6 视网膜的散射 2+GF:[$ ){>;eky 在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 `>8| ?k_=?m -lMC{~h\(S 图4. 视网膜朗伯散射设定 [-$&pB>w8' 注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 l:HO|Mq
X2i<2N*@ u 3,b,p 图5. 视网膜重点采样规格设定 oqDW}>. 脚本 FZA8@J|Q4 /p>"|z 内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: ]jHB'Y 8`VMdo9 图6. 用户对话框的创建与编辑 3<+l.Wly 图7. 用户对话框编辑器 v&XG4 & 如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 !gf&l ^) 余下的脚本计算与屈光度有关的所有参数。 l.BSZhO$ &9s6p6eb 分析 hkU#
lt il-&d]AP 屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 Vn/6D[}Tu XY4s 图7. 字母F在视网膜上颜色分析 RV(}\JU 脚本代码 *=/XlSWF u khI#:[ Option Explicit 'Remove this to enable non-dimensioned variables to be used. ^1cqx]>E )edM@beY_ Dim entity As T_ENTITY e('c9 Y Dim op As T_OPERATION aYj3a;EmU Dim mat As T_MODELMATERIAL N M8F Dim A As Double $e*Nr=/ Dim pupilDiam As Double Pm?6]] 7 Dim eID As Long ,Fr{i1Ky Dim parID As Long ~!A,I 9 Dim count As Integer Pucf0 # Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double 9i`LOl:; Dim tlens As Double, nlens As Double `P z !H Dim curv As Double, conic As Double IWT##']G Dim ok As Long r>)\"U# x9_ Lt4 Sub Main v}_$9&|S Q49|,ou[H '用户输入对话框 "Z{^i3gN Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 {9l4 pT3 TextBox 220,21,40,21,.TextBox1 'default: 0 84knoC Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 bm+ Mr OKButton 40,91,90,21 v%FVz CancelButton 190,91,90,21 @P.l8|w Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 2hpx%H TextBox 220,49,40,21,.TextBox2 'default: 4 ^2??]R&Q
End Dialog W"Rii]GK" Dim dlg As UserDialog U50X`J rzTyHK[ ok = Dialog (dlg) }%1E9u ZbGyl}8ua If ok=0 Then 'cancel button was pressed vv8$u3H Print "Execution cancelled." Z0'3.D,l End Yj"UD:p End If { &qBr&kg v[|iuOU 'Assign accommodation and pupil diameter & use defaults if field left empty cu"%>>,, If dlg.TextBox1 = "" Then eP2 y U A = 0 'Default accommodation vB
Jva8;Q Else *m"mt A = CDbl(dlg.TextBox1) A|&EI-In End If T#BOrT>V 1Jd: %+T If dlg.TextBox2 = "" Then 1=D!C lcb pupilDiam = 4 'Default pupil diameter :qZ^<3+: Else )b7mzDp( pupilDiam = CDbl(dlg.TextBox2) =['ijD4TW End If cnc$^[c z]WT>4 Print " " ec0vg.>p Print "Accommodation = " & A & " Diopters" _YJw F1e+M Print "Pupil Diameter = " & pupilDiam & " mm" -?(RoWv@X& Ya. $x~ ' Calculate new parameters with accommodation Lf-8G5G taq = 0.55 + 2.97 - 0.04*A 'Aqueous thickness Q d./G5CC bk?\=4B:E Rant = 12.0 - 0.4*A 'Radius of anterior lens b?^n'0 CCant = -7.518749 + 1.285720*A 'Conic constant of anterior lens +?<jSmGW QCo^#- Rpost = -5.224557 + 0.2*A 'Radius of posterior lens l>iU Q&V CCpost = -1.353971 - 0.431762*A 'Conic constant of posterior lens r%#qbsN F,zJdJ tlens = 3.767 + 0.04*A 'Lens thickness /7#&qx8 Yru[{h8hw` nlens = 1.42 + 0.00256*A - 0.00022*A^2 'Lens index of refraction xH0/R LK3J 4{?x(~ 'Adjust parameters to account for accommodation %;5hHRA [Ok8l=' '************************************************************************* $>UzXhf}\ 'Aqueous thickness (Position of Lens) hJ<2bgQo '************************************************************************* dF,FH- eID = FindFullName( "Geometry.Arizona Eye.Lens" ) r &[~/m8zl GetCustomElement eID, entity ~<%cc+;` UE4#j\ parID = FindFullName( "Geometry.Arizona Eye" ) W% [5~N ,54<U~Lg: ' Delete any shift(s) in z x\DkS,O count = 0 wl%1B64
While GetOperationCount(eID)>count hF~B&^dd. GetOperation eID, count, op f3>/6C If op.Type="ShiftZ" Then _:L*{=N DeleteOperation eID,count H1[aNwLr count=count-1 ~roHnJ> End If R}>Do=hAO count=count+1 `O{Uz?#*x Wend l)8 V:MK >DRs(~|V# 'Set new shift in +7^Ul6BB#K op.Type = "ShiftZ" ^ztf:'l@C op.val1 = taq O5Lv:qAa op.parent = parID 0Nu]N)H5<l AddOperation eID, op *ls6#j@ Print "Set aqueous humor thickness = " & taq-0.55 a{+oN
$ }'W^Ki$ '************************************************************************* }WbN) 'Radius and conic constant of anterior lens l.x }I"tf '************************************************************************* FQFENq''B eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) 8j}m\^si GetConic eID, entity, curv, conic 6dL>Rzl$Dk \bOjb\ w$ SetConic eID, entity, 1/Rant, CCant r!^\Q7 Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant b-?o?}* w8
$Qh%J'< '************************************************************************* %SGO"*_ 'Radius and conic constant of posterior lens <.b$
gX '************************************************************************* ^wa9zs2s;/ eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) [,^dM:E/ GetConic eID, entity, curv, conic Lf#G?]@ Y14R"*t~ SetConic eID, entity, 1/Rpost, CCpost 1Q SIZoK7 Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost >@U<?wP Rda1X~-g '************************************************************************* p2vBj. *J 'Lens thickness (Position of posterior lens surface) Nr9[Vz?$P '************************************************************************* /8}+#h)[ S I7B6c parID = FindFullName( "Geometry.Arizona Eye.Lens" ) \`&pk-uW Y:%)cUxA ' Delete any z-shift(s) +^?-}v count = 0 N[bN"'U/1 While GetOperationCount(eID)>count dyzwJ70K GetOperation eID, count, op OLNn3
J If op.Type="ShiftZ" Then /K) b0QX DeleteOperation eID,count <IyLLQ+v count=count-1 ^-GX&ODa End If Qz+d[%Q}x count=count+1 @>2rz Wend xm|4\H&Bg m5w9l"U]H 'Set new z-shift )8 :RiG2B op.Type = "ShiftZ" ~'J =!Xy op.val1 = tlens I`W-RWZ op.parent = parID :ECK
$Cu AddOperation eID, op Y-q@~vZ] Print "Set lens thickness = " & tlens BhW]Oq& x}<G!*3 '************************************************************************* &8+6!TN7 'Lens index of refraction ,{?bM '************************************************************************* d Zz^9:C+ eID = FindMaterial( "Lens" ) CY3 \:D0I GetModelMaterial eID, mat &n]Z1e}5 :Q
?J}N mat.Nd = nlens OF<n T SetModelMaterial eID, mat o|qeh<2=x Print "Set lens index of refraction = " & nlens 'Z2N{65 QP5:M!O<) '************************************************************************* EO/cW<uV' 'Pupil diameter "1!.^<V* '************************************************************************* V,XP&,no\j eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) 8U2wH B:- KZuO 'Adjust pupil diameter (trimming volume inner hole) ~|Ih
JzDt EB2^]? SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" ;}eEG{`Y 7tl)4A6 ' Adjust pupil location to just in front of the lens K;y\[2;}e, parID = FindFullName( "Geometry.Arizona Eye" ) !|<f%UO eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) Wqs.oh count = 0 :qCm71* While GetOperationCount(eID)>count I0l.KiBm GetOperation eID, count, op DA MpR3 If op.Type="ShiftZ" Then _UBJPb@=U DeleteOperation eID,count /cL9?k;o count=count-1 [wy3Ld End If ;h-G3>Il count=count+1 /[|}rqX( Wend U.pr} hq op.Type = "ShiftZ" e(n2+S#N op.val1 = taq-0.01 TFJ{fLG op.parent = parID Sa[EnC AddOperation eID, op j |'#5H` v[,v{5b Print "Set pupil diameter = " & pupilDiam P96Cw~<Q? 7:VEM;[d 'Update AZ Eye subassembly Description S0.- >"L eID = FindFullName( "Geometry.Arizona Eye" ) U/3e,`c GetEntity eID, entity k\Z;Cmh> entity.Description = "Accommodation = " & A & "D" cu479VzPx: SetEntity eID, entity 0K$WSGB?6j ^;)SFmjg% Update (Y'UvZlM%P Print "DONE!" q-3J.VLJ5H SA`J.4yn End Sub Pa+AF v E3{H 如果屈光度是4,光瞳直径是4,则会输出如下数据: c+E//X| DV7<n&P Accommodation = 4 Diopters k5fH; Pupil Diameter = 4 mm rY[3_ NG% Set aqueous humor thickness = 2.81 sxN>+v11z Set anterior lens radius = 10.4 and conic constant = -2.375869 m0BG9~p| Set posterior lens radius = -4.424557 and conic constant = -3.081019 a8bX"#OR&N Set lens thickness = 3.927
+eDN,iv Set lens index of refraction = 1.42672 ^B<PD] Set pupil diameter = 4 {hs2?#p DONE! ubzb kH>vD =q> (文章来源:讯技光电)
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