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简介 0o$HC86w 人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 kr`BUW3 `ab\i`g9 模型 ([CnYv AJ`
v 模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 `vxrC&,As XQJ^)d00h Table 1. AZ眼睛模型的定义 lhA
s!\F 在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. j$8|ym^OX 4_762Gu% 光源 +%qSB9_>N{ <S8W~wC 多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 kad;Wa#h ^GrkIh0nL 3).o"AN 图1. 光源和提示信息使用 W+f&%En 除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 +#uNQ`1v /1W7<']>xV 在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 ,J(5@8(>a NVc!g 图2. 字母F光源的设定方法光 7vpN6YP u:uSsAn0$ 图3. 字母F在视网膜上位置点列图 g{W6a2 视网膜的散射 $JhZ'Z TjUZv 1(L 在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 ;*-@OLT_K \l]pe|0EW +dgo-)kP(_ 图4. 视网膜朗伯散射设定 /iTUex7T 注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 @nx}6?p\, 8PoHBOxpc hX8gV~E=y 图5. 视网膜重点采样规格设定 ;o)=XEh8P 脚本 U +*oI * &V#z kW 内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: Z<N&UFw7QJ =(.mf 图6. 用户对话框的创建与编辑 ;c X^8;F0 图7. 用户对话框编辑器 G/fP(o-Wd 如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 YBtq0c 余下的脚本计算与屈光度有关的所有参数。 J+@MzkpK 1<W4>~,wj 分析 :m*!?QGdL GSGyF 屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 \,l.p_< [ZKtbPHb 图7. 字母F在视网膜上颜色分析 K_AtU/ 脚本代码 )l#%.Z9 (ET ;LH3 Option Explicit 'Remove this to enable non-dimensioned variables to be used. <+T\F; `J>E9p< Dim entity As T_ENTITY s%N` Dim op As T_OPERATION ~m?74^ i Dim mat As T_MODELMATERIAL <78$]Z2we Dim A As Double %tzN@ Dim pupilDiam As Double >'} Y1_S5 Dim eID As Long q GpP, Dim parID As Long ;|>q zx Dim count As Integer ?w]"~ Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double {PODisl>\D Dim tlens As Double, nlens As Double sf |oNOz Dim curv As Double, conic As Double ( zn_8s Dim ok As Long I&TTr7 Wl&
>6./{ Sub Main (s}Rj)V[^ 2^)D
.& '用户输入对话框 t]
r,9df' Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 cBz!U8( TextBox 220,21,40,21,.TextBox1 'default: 0 7tpAZ<{ Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 35Ai;mU' OKButton 40,91,90,21 BIxV|\k CancelButton 190,91,90,21 2BoFyL* Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 :y+B;qw TextBox 220,49,40,21,.TextBox2 'default: 4 IL~]m?'V( End Dialog (3
IZ Dim dlg As UserDialog Ur'9bl{5 7?6xPKQ)H ok = Dialog (dlg) 81GQijq #4P8Rzl$/ If ok=0 Then 'cancel button was pressed *Q bM*oH Print "Execution cancelled." H$z>OS_6U End { 1+Cw?1d End If LP.HS'M~u PD6MyW05%9 'Assign accommodation and pupil diameter & use defaults if field left empty 8weSrm If dlg.TextBox1 = "" Then x96qd%l/ A = 0 'Default accommodation B#FHf
Z Else _1I K$gb[ A = CDbl(dlg.TextBox1) .)LZ`Ge3F End If YV5Yx-+3w$ v6wRME;JA If dlg.TextBox2 = "" Then J.1O/Pw!.a pupilDiam = 4 'Default pupil diameter kUNj4xp) Else z%OuI 8"' pupilDiam = CDbl(dlg.TextBox2) $Mdbto~ < End If R'rTE ;tJWOm Print " " %lN2n,AK Print "Accommodation = " & A & " Diopters" "yg.hK` Print "Pupil Diameter = " & pupilDiam & " mm" 8O,?|c=> h,^BC^VU9- ' Calculate new parameters with accommodation TqIAWbb& taq = 0.55 + 2.97 - 0.04*A 'Aqueous thickness ?nQ_w0j $z*@2Non Rant = 12.0 - 0.4*A 'Radius of anterior lens j]rXoV> CCant = -7.518749 + 1.285720*A 'Conic constant of anterior lens 2zz,(RA +`ai1-vw Rpost = -5.224557 + 0.2*A 'Radius of posterior lens js~tKUvg CCpost = -1.353971 - 0.431762*A 'Conic constant of posterior lens YPu9Q lK0s=4c{ tlens = 3.767 + 0.04*A 'Lens thickness 59.$ULQVMY M|d={o9Hp nlens = 1.42 + 0.00256*A - 0.00022*A^2 'Lens index of refraction vB^uxdt|m 'iJDWxCD 'Adjust parameters to account for accommodation f0vJm #,G1R7 '************************************************************************* u^Vh.g] 'Aqueous thickness (Position of Lens) cv2]* '************************************************************************* ^EF'TO$ eID = FindFullName( "Geometry.Arizona Eye.Lens" ) zJ;Rt9<7- GetCustomElement eID, entity FKC\VF 9 CB\n parID = FindFullName( "Geometry.Arizona Eye" ) xOythvO tR1FO%nC ' Delete any shift(s) in z ^=^$tF count = 0 E!zX)|Z< While GetOperationCount(eID)>count 3)3Hck
GetOperation eID, count, op %<ic%gt`# If op.Type="ShiftZ" Then D|l,08n"? DeleteOperation eID,count )>\4ULR83 count=count-1 zN%97q_ End If Y6A;AmM8 count=count+1 @xS]!1- Wend ND5$bq Nu? =Q-k'= 6\ 'Set new shift in 3Hw[s0[$ op.Type = "ShiftZ" +TH3&H5I_A op.val1 = taq ?n.)&ZIx0 op.parent = parID >.e+S?o AddOperation eID, op 6W&_2a7* Print "Set aqueous humor thickness = " & taq-0.55 -p`L%xj\ NgVR,G|1 '************************************************************************* ,X68xk.' 'Radius and conic constant of anterior lens OUI6
ax\[ '************************************************************************* iCP~O eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) Ow@v"L;jF! GetConic eID, entity, curv, conic F)SP aC4 ^]>aHz9 SetConic eID, entity, 1/Rant, CCant je%l dY]/@ Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant :HRT 2I E)W@{?.o# '************************************************************************* )6-9)pH@) 'Radius and conic constant of posterior lens W\8Ln> '************************************************************************* oh~:, eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) +Rwx%= GetConic eID, entity, curv, conic x GH1epf /:Lu_)5 SetConic eID, entity, 1/Rpost, CCpost 6S1m<aH6 Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost 8AL\ST51x" l+'F_a '************************************************************************* d(;4`kd*N 'Lens thickness (Position of posterior lens surface) M:n 6BC>t" '************************************************************************* Zgamd1DJ[l c?E{fD"Fc3 parID = FindFullName( "Geometry.Arizona Eye.Lens" ) NmpnJu|8 0 )}$^TV ' Delete any z-shift(s) z wk.bf>m count = 0 =:=/Gz1 While GetOperationCount(eID)>count o&SSvW GetOperation eID, count, op <jA105U"m> If op.Type="ShiftZ" Then [syj# DeleteOperation eID,count j}f[W [2 count=count-1 5M F#&v End If H'DVwnn>ik count=count+1 )OP){/ Wend S,{tV=&m] @Jn!0Y1_3 'Set new z-shift xZ .!d.rn op.Type = "ShiftZ" wTc)S6%7 op.val1 = tlens ' cIEc1y op.parent = parID h8{(KRa 6 AddOperation eID, op O_~7Glu Print "Set lens thickness = " & tlens n3KI+I%nQ #7G*GbKY '************************************************************************* ~h$wH{-U# 'Lens index of refraction 5(m(xo6 '************************************************************************* l\OLyQ eID = FindMaterial( "Lens" ) `A@w7J' GetModelMaterial eID, mat BuOgOYh9 6.WceWBR mat.Nd = nlens 'b&yrBFD SetModelMaterial eID, mat m Y,|J\w@ Print "Set lens index of refraction = " & nlens K > g[k_ =r2]uW9 '************************************************************************* L2UsqVU 'Pupil diameter x;s0j"`Jb '************************************************************************* % Zjdl eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) j<<3Pr q5DEw&UZJ 'Adjust pupil diameter (trimming volume inner hole) tc+WWDP#" w_tJ7pz8T SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" 88s/Q0l U8$4
R,+ ' Adjust pupil location to just in front of the lens p4!:]0c parID = FindFullName( "Geometry.Arizona Eye" ) _}xd}QW eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) OHv! count = 0 ^D%Za' While GetOperationCount(eID)>count =c.5874A` GetOperation eID, count, op 2,q}Nq If op.Type="ShiftZ" Then }_9,w;M$ DeleteOperation eID,count =FP0\cQ. count=count-1 co8"sz0(U End If as yZe count=count+1 ia @'%8 Wend >Gml4vGK op.Type = "ShiftZ" i%m"@7.kk op.val1 = taq-0.01 8,P-
7^ op.parent = parID b;sVls AddOperation eID, op \_V-A f{6 HBS\<} Print "Set pupil diameter = " & pupilDiam w'MGA RD7^& 'Update AZ Eye subassembly Description aT!'}GjL eID = FindFullName( "Geometry.Arizona Eye" ) OJ|r6 GetEntity eID, entity x+8_4>,>Y7 entity.Description = "Accommodation = " & A & "D" yZr M.%V SetEntity eID, entity ^&@w$ ?'86d_8 Update K_)eWf0a Print "DONE!" l/TjQ* e}/Lk5q! End Sub TxjYrzC a7zcIwk
'{ 如果屈光度是4,光瞳直径是4,则会输出如下数据: m7a#qs;, )c n+1R Accommodation = 4 Diopters KqBk~-G Pupil Diameter = 4 mm xsd_Uu* Set aqueous humor thickness = 2.81 y&}E~5O Set anterior lens radius = 10.4 and conic constant = -2.375869
{vUN+We Set posterior lens radius = -4.424557 and conic constant = -3.081019 u0aJu Set lens thickness = 3.927 %~L>1ShtU Set lens index of refraction = 1.42672 ;c~cet4 Set pupil diameter = 4 m8'C_U^89 DONE! :I -V_4b `>0MNmu (文章来源:讯技光电)
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