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    [技术]Arizona眼睛模型 [复制链接]

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    离线infotek
     
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    只看楼主 倒序阅读 楼主  发表于: 2021-10-22
    简介 , }xpYq_/  
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    人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 ,6cbD  
    F3H:I"4  
    模型 ;XKo44%  
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    模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 / y":/" h  
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    Table 1. AZ眼睛模型的定义
    h&:Q$*A>   
    在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. v4Fnh`{  
     \\E_W9.u  
    光源 s)`1Rf  
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    多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 cLN[o8 ZU  
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    图1. 光源和提示信息使用
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    除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 Jnu}{^~  
    /64^5DjTh  
    在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 n+RUPZ  
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    图2. 字母F光源的设定方法光 #1,>Qnl  
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    图3. 字母F在视网膜上位置点列图
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    视网膜的散射 709Uv5  
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    在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 YWn6wzu%Vc  
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    图4. 视网膜朗伯散射设定
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    注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 [M8qU$&?]  
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    图5. 视网膜重点采样规格设定
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    脚本 4LB9w 21  
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    内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: ixI5Xd<  
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    图6. 用户对话框的创建与编辑
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    图7. 用户对话框编辑器
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    如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 ;&t1FH#=  
    余下的脚本计算与屈光度有关的所有参数。 ^&Rxui  
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    分析 Oa_o"p<Lr  
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    屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 }:c,S O!  
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    图7. 字母F在视网膜上颜色分析
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    脚本代码 }T1Xds8w)t  
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    Option Explicit     'Remove this to enable non-dimensioned variables to be used. b1 ['uJF  
    ^?S@v1~7d  
    Dim entity As T_ENTITY L_zmU_zD  
    Dim op As T_OPERATION (J;zkb  
    Dim mat As T_MODELMATERIAL *l'$pJ X  
    Dim A As Double MIXrLh3  
    Dim pupilDiam As Double dc@wf;o  
    Dim eID As Long T~ q'y~9o  
    Dim parID As Long glKs8^W  
    Dim count As Integer as\K(c9  
    Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double tx&U"]  
    Dim tlens As Double, nlens As Double /CQQ^/  
    Dim curv As Double, conic As Double V.a]IkK'K  
    Dim ok As Long n+F-,=0  
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    Sub Main jv#" vQ9A]  
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        '用户输入对话框 )}9}"jrDlx  
        Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 7J!d3j2TR  
            TextBox 220,21,40,21,.TextBox1 'default: 0 K&P{2Hndr  
            Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 ~9/nx|%D  
            OKButton 40,91,90,21 vJj j+:  
            CancelButton 190,91,90,21 *y\tnsU  
            Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 0&L0j$&h  
            TextBox 220,49,40,21,.TextBox2 'default: 4 ^{sI'l~  
        End Dialog |u@>[*k'=  
        Dim dlg As UserDialog [j+0EVwB  
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        ok = Dialog (dlg) YrcC"  
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        If ok=0 Then    'cancel button was pressed T9;o.f S  
            Print "Execution cancelled." _itN.^  
            End T+{'W  
        End If XxU}|jTO#  
    89e.\EH  
        'Assign accommodation and pupil diameter & use defaults if field left empty Ex&RR< 5  
        If dlg.TextBox1 = "" Then 0c;"bA0>Sx  
            A = 0           'Default accommodation n\)f.}YD8d  
        Else ~~E=E;9  
            A = CDbl(dlg.TextBox1) ] 8cX#N,M  
        End If zs^\z Cb8  
    |0 pBBDw  
        If dlg.TextBox2 = "" Then NU\t3JaR  
            pupilDiam = 4   'Default pupil diameter $gtT5{"PN(  
        Else Z5^ UF2`Q  
            pupilDiam = CDbl(dlg.TextBox2) GKDG5u;  
        End If xMGd'l?  
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        Print " " v__Go kj-  
        Print "Accommodation = " & A & " Diopters" R =c  
        Print "Pupil Diameter = " & pupilDiam & " mm" ]CJ>iS!V  
    r ($t.iS  
        ' Calculate new parameters with accommodation iQR})=Q  
        taq = 0.55 + 2.97 - 0.04*A              'Aqueous thickness 'eXw`kw(  
    O9IjU10:  
        Rant = 12.0 - 0.4*A                     'Radius of anterior lens x@\'@>_GM  
        CCant = -7.518749 + 1.285720*A          'Conic constant of anterior lens 5GpKX  
    Z]+Xh  
        Rpost = -5.224557 + 0.2*A               'Radius of posterior lens -Z& {$J  
        CCpost = -1.353971 - 0.431762*A         'Conic constant of posterior lens  2x J5  
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        tlens = 3.767 + 0.04*A                  'Lens thickness ,<WykeC  
    !7kOw65+0  
        nlens = 1.42 + 0.00256*A - 0.00022*A^2  'Lens index of refraction 'WgwLE_  
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        'Adjust parameters to account for accommodation pKlT.<X7  
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        '************************************************************************* W n mRRq^  
        'Aqueous thickness (Position of Lens) @G{DOxE*  
        '************************************************************************* P@![P Ij  
        eID = FindFullName( "Geometry.Arizona Eye.Lens" ) 7i8qB462  
        GetCustomElement eID, entity +~AI(h  
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        parID = FindFullName( "Geometry.Arizona Eye" ) Hx0,kOh)  
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        ' Delete any shift(s) in z 5Rp2O4Z  
        count = 0 #iU/Yg!  
        While GetOperationCount(eID)>count ~"B[6^sW  
            GetOperation eID, count, op Nr+1N83S}  
            If op.Type="ShiftZ" Then >#|Q,hVU5  
                DeleteOperation eID,count #ms98pw%5  
                count=count-1 c?Qg :yU  
            End If 8TvPCZ$x  
            count=count+1 J#WPXE+Ds  
        Wend \F3t&:  
    pQ\ [F  
        'Set new shift in '2#fkH[.  
        op.Type = "ShiftZ" 5ZxBmQ  
        op.val1 = taq jO.E#Ei}~  
        op.parent = parID r!uAofIi_  
        AddOperation eID, op S"z4jpqn3  
        Print "Set aqueous humor thickness = " & taq-0.55 @vh>GiR){  
    DF =. G1  
        '************************************************************************* s3^SjZb  
        'Radius and conic constant of anterior lens |Ay#0uQ5Y  
        '************************************************************************* 5xKR ]u  
        eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) Pl6=._  
        GetConic eID, entity, curv, conic v836nxLM  
    nQ6'yd"  
        SetConic eID, entity, 1/Rant, CCant VG^-aR_F  
        Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant _m-r}9au   
    vX%gcs/@  
        '************************************************************************* 95&HsgdxJ  
        'Radius and conic constant of posterior lens P.7B]&T6  
        '************************************************************************* c6|&?}F  
        eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) .&dcJh*O+  
        GetConic eID, entity, curv, conic S3f BZIPp  
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        SetConic eID, entity, 1/Rpost, CCpost WG n1pW  
        Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost Y8(yOVy9  
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        '************************************************************************* }OFk.6{{&v  
        'Lens thickness (Position of posterior lens surface) `^[ra% a  
        '************************************************************************* X}Fv*  
    L|?tcic  
        parID = FindFullName( "Geometry.Arizona Eye.Lens" ) Y8T.RS0  
    10 ^=1@U  
        ' Delete any z-shift(s) @pz2}Hd |  
        count = 0 v\C+G[MV 7  
        While GetOperationCount(eID)>count *<1m 2t>.  
            GetOperation eID, count, op z_)$g= 9$  
            If op.Type="ShiftZ" Then qE[}Cf]X  
                DeleteOperation eID,count NKws;/u  
                count=count-1 ?1sY S  
            End If 3t'K@W?AJh  
            count=count+1 M\3!elp2z  
        Wend XRkqMq%  
    %LyB~X  
        'Set new z-shift u9Ro=#xt  
        op.Type = "ShiftZ" 9q?gmAn.  
        op.val1 = tlens >qla,}x  
        op.parent = parID Q@R8qc=*  
        AddOperation eID, op  "(xu  
        Print "Set lens thickness = " & tlens 78wcMQNX9  
    kQ+5p Fo3  
        '************************************************************************* 04:Dbt~=?p  
        'Lens index of refraction y\x<!_&D  
        '************************************************************************* r%4:,{HF  
        eID = FindMaterial( "Lens" ) YeVhWPn@  
        GetModelMaterial eID, mat % |V:F.f  
    9w1)Mf}  
        mat.Nd = nlens ~n?U{ RmH  
        SetModelMaterial eID, mat u CXd% CzE  
        Print "Set lens index of refraction = " & nlens xS'So7:h  
    U,N4+F}FR  
        '************************************************************************* (,>`\\  
        'Pupil diameter  `S|gfJ  
        '************************************************************************* #,sJd^uI  
        eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) 4p]Y`];U  
    $HRpG  
        'Adjust pupil diameter (trimming volume inner hole) +t f=  
    S1."2AxO  
        SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" ocvBKsfhE`  
    A<&9   
        ' Adjust pupil location to just in front of the lens x =k$^V~  
        parID = FindFullName( "Geometry.Arizona Eye" ) `?:'_K i  
        eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) BLRrHaX0  
        count = 0 %2.T1X%!  
        While GetOperationCount(eID)>count :}lE@Y,R   
            GetOperation eID, count, op 8cHZBM7'  
            If op.Type="ShiftZ" Then "F^EfpcJ{9  
                DeleteOperation eID,count Oe?nX>  
                count=count-1 =vWnqF:  
            End If  F#hM S<  
            count=count+1 wBf bpoE7  
        Wend *+G K ?Ga  
        op.Type = "ShiftZ" /cg!Ap5  
        op.val1 = taq-0.01 A /MOY@%G  
        op.parent = parID ,xiRP$hGhh  
        AddOperation eID, op ^0 t`EZ$  
    wG B'c's*  
        Print "Set pupil diameter = " & pupilDiam nv={.H  
    W{%M+a[#l  
        'Update AZ Eye subassembly Description Gfvz%%>l  
        eID = FindFullName( "Geometry.Arizona Eye" ) eu~;G H  
        GetEntity eID, entity *ULXJZ%  
        entity.Description = "Accommodation = " & A & "D" Sdn] f4  
        SetEntity eID, entity :=/DF  
    `f (!i mN  
        Update `hbM 2cM  
        Print "DONE!" U|>Js!$  
         W uQdz&s>  
    End Sub *Hs5MXNu  
    Y{jhT^tKK  
    如果屈光度是4,光瞳直径是4,则会输出如下数据: x@/ !H<y  
    [=iq4F'7  
    Accommodation = 4 Diopters V/03m3!q  
    Pupil Diameter = 4 mm dCinbAQ  
    Set aqueous humor thickness = 2.81 _|F h^hq  
    Set anterior lens radius = 10.4 and conic constant = -2.375869 zUOYH4+  
    Set posterior lens radius = -4.424557 and conic constant = -3.081019 b_B4  
    Set lens thickness = 3.927 MT3UJ6~P  
    Set lens index of refraction = 1.42672 ]UNmhF!W>u  
    Set pupil diameter = 4 !l}es4~.a  
    DONE! <|{=O9  
     
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