2WYPO"q 人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 Aj]V`B:65 'K,:j 388 模型 ."y1_dDql by/jYg)+ 模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 Y,zxbXZv'5 Table 1. AZ眼睛模型的定义 K0Fh%Y4)QH l0A&9g*l2 在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. \d$!a5LF} _b;{_g 光源 /FEVmH?
aPbE;"
f 多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 I"7u2"@-8j ,{?%m6.lE 图1. 光源和提示信息使用 h2;F 7o5BXF 除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。
_~ iw[*#u $[=%R`~w 在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 ]}2ZttQ? 图2. 字母F光源的设定方法光 Otm0(+YB7
t[
C/
图3. 字母F在视网膜上位置点列图 _[ZO p ~ LOV)3{m 视网膜的散射 zu|\fP s(q_
o 在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 t"/q]G5 M} v/tRI 图4. 视网膜朗伯散射设定 =^ 50FI| agW@{c 注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 AoL2@C.C%D +@iA;2& 图5. 视网膜重点采样规格设定 ur7q [n )iK6:s# 脚本 H-f X(9 um>6z_" 内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: ,>+p-M8ZL 图6. 用户对话框的创建与编辑 Q9G;V]./ 图7. 用户对话框编辑器 FZE"7ec>m mk+B9?;cF- 如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 ?|B&M\}g 余下的脚本计算与屈光度有关的所有参数。 N7
$I^?< 2Gaa(rJ5o 分析 JKGe" T\>a! 屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 'o>B'$ 图7. 字母F在视网膜上颜色分析 i5?q,_ &t:Gx<] 脚本代码 6- B|Y3)B :\7X}n*& Option Explicit 'Remove this to enable non-dimensioned variables to be used. vJOw]cwq (7=!+'T" Dim entity As T_ENTITY o:P}Wg/NK Dim op As T_OPERATION Hm'=aff6A Dim mat As T_MODELMATERIAL 6 EC* Dim A As Double 3/W'V,5G6 Dim pupilDiam As Double Opc
ZU{4b Dim eID As Long 0-yp,G Dim parID As Long z]`k#O%%) Dim count As Integer ktBj|-'> Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double !sW(wAy?o Dim tlens As Double, nlens As Double
^J)mH[ Dim curv As Double, conic As Double $jqq
`n_ Dim ok As Long fbKkq.w 8=uu8-l8g Sub Main 6){]1h" ?FF4zI~ '用户输入对话框 9}F*P669f Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 [dIXR TextBox 220,21,40,21,.TextBox1 'default: 0 x&Kh>PVh\ Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 w\i\Wp,FP OKButton 40,91,90,21 EZ$>.iy{ CancelButton 190,91,90,21 22M1j5 Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 A5R<p+t6 TextBox 220,49,40,21,.TextBox2 'default: 4 K<qk.~
S End Dialog OJ5#4qJ[ Dim dlg As UserDialog sjwo/+2 F{~{Lthc ok = Dialog (dlg) ,*hLFaR- ![_*(8v}S If ok=0 Then 'cancel button was pressed KZ
;k)O.Ov Print "Execution cancelled." N&g3t%F End "(z5{z?S End If 6GSI"M6s mmEYup(l0; 'Assign accommodation and pupil diameter & use defaults if field left empty 7k9G(i[-+ If dlg.TextBox1 = "" Then RcM/!,B A = 0 'Default accommodation [~#WG/!: Else *|C^=*j9 A = CDbl(dlg.TextBox1) }v!$dr,j' End If QaS7z#/?. B43HNs If dlg.TextBox2 = "" Then W=Mb pupilDiam = 4 'Default pupil diameter {kCw+eXn? Else pg.ri64H< pupilDiam = CDbl(dlg.TextBox2) J^}V|# End If
(SDr!!V< `YLD`(\ Print " " Q$1bWUS& Print "Accommodation = " & A & " Diopters" 8WbgSY` Print "Pupil Diameter = " & pupilDiam & " mm" Vp*KfS] SmdjyK1~8 ' Calculate new parameters with accommodation $M lW4&a| taq = 0.55 + 2.97 - 0.04*A 'Aqueous thickness bE#,=OI$ .
Z.)t Rant = 12.0 - 0.4*A 'Radius of anterior lens uK$9Ll{lk CCant = -7.518749 + 1.285720*A 'Conic constant of anterior lens ,)Ju [ 1#*a:F&re Rpost = -5.224557 + 0.2*A 'Radius of posterior lens 1[qLA!+ CCpost = -1.353971 - 0.431762*A 'Conic constant of posterior lens [los dnH^? K/b_22]CC tlens = 3.767 + 0.04*A 'Lens thickness
1 +qw$T y?m/*hh` nlens = 1.42 + 0.00256*A - 0.00022*A^2 'Lens index of refraction d + / &?3 wF,UE_ 'Adjust parameters to account for accommodation L[H5NUG! h[1MtmNw '************************************************************************* ujaGNg?, 'Aqueous thickness (Position of Lens) Co9QW/'i '************************************************************************* R)z4n eID = FindFullName( "Geometry.Arizona Eye.Lens" ) RHq/JD- GetCustomElement eID, entity 2FF4W54I RwPN gRF parID = FindFullName( "Geometry.Arizona Eye" ) P 8>d6;o($ YN2sdG ' Delete any shift(s) in z X*39c
b(b count = 0 g[Ib,la_a While GetOperationCount(eID)>count RGg(%. GetOperation eID, count, op NufLzg{ If op.Type="ShiftZ" Then 8X`tU<Ab DeleteOperation eID,count LbG_ z =A count=count-1 3k#/{Z End If Bck7\ count=count+1 #u"k~La Wend m&\h4$[kql f3{MvAy[ 'Set new shift in 9C[ywp op.Type = "ShiftZ" gu<'QV" op.val1 = taq PBxCx3a{ op.parent = parID ;A'Z4=*~ AddOperation eID, op \2}bi:e6 Print "Set aqueous humor thickness = " & taq-0.55 .J.-Mm`. 079'(% '************************************************************************* gk+h8 LZ 'Radius and conic constant of anterior lens C;`XlQG ` '************************************************************************* w{uuSe eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) a,+@|TJ,i GetConic eID, entity, curv, conic A~+S1 2fS[J'-o SetConic eID, entity, 1/Rant, CCant 4Hn`'+b Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant 2KN6} %]6~Eq%s '************************************************************************* {h2TD
P 'Radius and conic constant of posterior lens r8&^>4 '************************************************************************* <Ib[82PU eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) &jczO-R^ GetConic eID, entity, curv, conic *
Y7jl#7 9D}/\jM SetConic eID, entity, 1/Rpost, CCpost t|!j2<e Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost OY5OJ* }kK[S|XVO '************************************************************************* 7&"n`@(.! 'Lens thickness (Position of posterior lens surface) Da:unVbU '************************************************************************* HXYRH ^Q ps>A( parID = FindFullName( "Geometry.Arizona Eye.Lens" ) ,4,V4 N +1!qs, ' Delete any z-shift(s) J}@z_^|"mJ count = 0 |'+eMl While GetOperationCount(eID)>count /`;n@0k>2 GetOperation eID, count, op D?,#aB" If op.Type="ShiftZ" Then pM&YXb? DeleteOperation eID,count hf<^/@^tK count=count-1 |vMpXiMxxT End If !!V#v9{ count=count+1 *" 98L+ Wend hj$e|arB f\1A!Yp 'Set new z-shift [NIlbjYH op.Type = "ShiftZ" f%)zg(YlO op.val1 = tlens %#Z/2<_ op.parent = parID zrv#Xa!O\ AddOperation eID, op ^eGNgE Print "Set lens thickness = " & tlens [kzd(u X _G| hx '************************************************************************* \U?n+6 7g 'Lens index of refraction 8W+gl=C~ '************************************************************************* <zy,5IlD eID = FindMaterial( "Lens" ) GF:`>u{C GetModelMaterial eID, mat GK}'R= 9F-
)r' mat.Nd = nlens P;8>5;U4- SetModelMaterial eID, mat s (LT Print "Set lens index of refraction = " & nlens KkMay =!UR=Hq '************************************************************************* ).HDru-2 'Pupil diameter J.+BD\pa '************************************************************************* c$,_>tcP eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) <U9/InN0[ J3b4cxm 'Adjust pupil diameter (trimming volume inner hole) 9
ASb>A2~ ph|ZG6: SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" $BDBN_p 4YMX|1wd) ' Adjust pupil location to just in front of the lens b*mKei parID = FindFullName( "Geometry.Arizona Eye" ) vhT_=:x eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) HygY>s+3[
count = 0 FNQX7O52 While GetOperationCount(eID)>count .LRxP#B GetOperation eID, count, op !lmWb-v%36 If op.Type="ShiftZ" Then s;YKeE!8 DeleteOperation eID,count rf9_eP count=count-1 @C-dG7U.P End If nCvPB/- count=count+1 ZRUhAp'<qj Wend /<3<.
~ op.Type = "ShiftZ" v !Kw<
fp| op.val1 = taq-0.01 Lj%{y.Rj op.parent = parID Y?r
po AddOperation eID, op FM5e+$>@ Zz |MIGHm Print "Set pupil diameter = " & pupilDiam &MgeYpd xaKst
p 'Update AZ Eye subassembly Description 6`"M eID = FindFullName( "Geometry.Arizona Eye" ) QI[}(O7#6 GetEntity eID, entity l??;3kh1 entity.Description = "Accommodation = " & A & "D" ,rwuy[Q8 SetEntity eID, entity tue/4Q#7 Ei@M$Fd Update 3Gr&p6 Print "DONE!" "x&C5l}n ;;gK@?hJ End Sub i(wgB\9i4 y9;#1:ic 如果屈光度是4,光瞳直径是4,则会输出如下数据: VzRx%j/i dj[apuiF Accommodation = 4 Diopters 9<]a!:!^ Pupil Diameter = 4 mm lZt(&^T Set aqueous humor thickness = 2.81 <3O T>E[ Set anterior lens radius = 10.4 and conic constant = -2.375869 P8gXCX!>U Set posterior lens radius = -4.424557 and conic constant = -3.081019 TQ1WVq
}* Set lens thickness = 3.927 #G,XDW2"w Set lens index of refraction = 1.42672 mf|pNiQ, Set pupil diameter = 4 g"!\\:M DONE! |